#8561. sTNFRII-Fc modification protects human UC-MSCs against apoptosis/autophagy induced by TNF-? and enhances their efficacy in alleviating inflammatory arthritis

October 2026publication date
Proposal available till 30-05-2025
4 total number of authors per manuscript3510 $

The title of the journal is available only for the authors who have already paid for
Journal’s subject area:
Biochemistry, Genetics and Molecular Biology (miscellaneous);
Medicine (miscellaneous);
Molecular Medicine;
Cell Biology;
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Abstract:
In this study, we examine how the use of soluble TNFR II can improve the course and outcomes of mesenchymal stem cell (MSC)-based therapy for autoimmune diseases, such as rheumatoid arthritis (RA) treatment, with a focus on the mechanism of soluble TNFR II.
Keywords:
Apoptosis; Autophagy; Genetic modification; Mesenchymal stem cells; Rheumatoid arthritis; sTNFRII-Fc; TNF-?

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