#3538. Utilising a systematic review-based approach to create a database of individual participant data for meta- and network meta-analyses: the RELEASE database of aphasia after stroke

October 2026publication date
Proposal available till 30-05-2025
4 total number of authors per manuscript0 $

The title of the journal is available only for the authors who have already paid for
Journal’s subject area:
Language and Linguistics;
Linguistics and Language;
LPN and LVN;
Otorhinolaryngology;
Developmental and Educational Psychology;
Neurology (clinical);
Neurology;
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Abstract:
Collation of aphasia research data across settings, countries and study designs using big data principles will support analyses across different language modalities, levels of impairment, and therapy interventions in this heterogeneous population. To report the development, preparation and establishment of an internationally agreed aphasia after stroke research database of individual participant data (IPD) to facilitate planned aphasia research analyses. Data were assessed for completeness, validity of value-ranges within variables, and described according to pre-defined categories of demographic data, therapy descriptions, and language domain measurements. We cleaned, clarified, imputed and standardised relevant data in collaboration with the original study investigators. The rigorous methodology for data acquisition and cleaning can serve as a template for the establishment of similar databases in other research areas.
Keywords:
aphasia; individual participant data; rehabilitation reporting standards; speech and language therapy; Stroke

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