#7244. Association of maternal pre-pregnancy dietary intake with adverse maternal and neonatal outcomes: A systematic review and meta-analysis of prospective studies

August 2026publication date
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Journal’s subject area:
Industrial and Manufacturing Engineering;
Food Science;
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Abstract:
This study aimed to summarize the evidence regarding the effects of dietary intake before conception on pregnancy outcomes by performing a systematic review and meta-analysis of prospective studies. With regard to maternal outcomes, pre-pregnancy intake of fried food, fast food, red and processed meat, hem iron and a low-carbohydrate dietary pattern was positively associated with the risk of gestational diabetes mellitus. However, a high dietary fiber intake and folic acid supplementation were negatively associated with gestational diabetes mellitus risk. With regard to neonatal outcomes, maternal caffeine intake before pregnancy significantly increased the risk of spontaneous abortion, while folic acid supplementation had protective effects on total adverse neonatal outcomes, preterm birth, and small-for-gestational age. However, no significant associations were found between adverse pregnancy outcomes and the pre-pregnancy dietary intake of sugar-sweetened beverages, potato, fish, and carbohydrates and the Healthy Eating Index.
Keywords:
maternal outcome; meta-analysis; neonatal outcome; Pre-pregnancy diet

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