#9322. Time-dependent changes in hippocampal and striatal glycogen long after maze training in male rats

August 2026publication date
Proposal available till 17-05-2025
4 total number of authors per manuscript4500 $

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Journal’s subject area:
Experimental and Cognitive Psychology;
Behavioral Neuroscience;
Cognitive Neuroscience;
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Abstract:
Long-lasting biological changes reflecting past experience have been studied in and typically attributed to neurons in the brain. Astrocytes, which are also present in large number in the brain, have recently been found to contribute critically to learning and memory processing. In the brain, glycogen is primarily found in astrocytes and is metabolized to lactate, which can be released from astrocytes. Here we report that astrocytes themselves have intrinsic neurochemical plasticity that alters the availability and provision of metabolic substrates long after an experience.
Keywords:
Astrocytes; Glycogen; Hippocampus; Lactate; Memory systems; Plasticity; Striatum

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