#9059. A Transdiagnostic Perspective on Youth Irritability

August 2026publication date
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4 total number of authors per manuscript3510 $

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Journal’s subject area:
Psychology (all);
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Abstract:
Irritability is increasingly recognized as a significant clinical problem in youth. It is a criterion for multiple diagnoses and predicts the development of a wide range of disorders. Research on its etiology suggests that genetic and family environmental factors play a role, as do abnormalities in reward and cognitive-control neural circuitry. However, many of these effects are age dependent. Threat-responsive self-regulatory systems and the degree to which irritability is tonic or phasic influence whether irritable youth exhibit more internalizing or more externalizing outcomes.
Keywords:
irritability; temper loss; transdiagnostic; youth

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