#8435. Selenium, a dietary-antioxidant with cardioprotective effects, prevents the impairments in heart rate and systolic blood pressure in adolescent rats exposed to binge drinking treatment

November 2026publication date
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Journal’s subject area:
Health Policy;
Medicine (miscellaneous);
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Abstract:
Heavy episodic or binge drinking causes cardiovascular alterations. Selenium with its antioxidant properties can help for correct the heart function. The study aims to investigate the protective cardiovascular effects of selenium under the BD-like procedure. Blood pressure and heart rate (HR) were determined after the experiments on adolescent rats. The following parameters were determined: Se deposits, oxidative balance, the expression of glutathione peroxidases (GPxs), NF-kB and caspase-3, DNA instability and serum vascular markers.
Keywords:
Binge drinking experience; heart rate; selenium; systolic blood pressure; vascular markers

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