#9424. Limited cheese intake reduces HPA axis and behavioral stress responses in male rats

November 2026publication date
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4 total number of authors per manuscript0 $

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Journal’s subject area:
Experimental and Cognitive Psychology;
Behavioral Neuroscience;
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Abstract:
Eating palatable foods reduces behavioral and hypothalamic-pituitary-adrenocortical (HPA) axis responses to stress – an idea referred to by the colloquial term “comfort” food. To study the underlying stress-relieving mechanisms of palatable foods, we previously developed a paradigm of limited sucrose feeding in which male rats are given twice-daily access to a small amount of sucrose drink and subsequently have reduced stress responses. Prior research in humans and rodents implicates high dietary sugars/carbohydrates with reduced stress responsivity. However, it is not clear whether the stress-relieving effects of the limited sucrose paradigm depend upon its macronutrient content. To test this idea, the current work measures stress responses in male rats following the limited intermittent intake of cheese – a highly palatable food that is low in sugar and other carbohydrates.
Keywords:
Anxiety-related behavior; Cheese; Corticosterone; Palatable food

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