#9423. Maternal deprivation induces cytoskeletal alterations and depressive-like behavior in adult male rats by regulating the AKT/GSK3?/CRMP2 signaling pathway

November 2026publication date
Proposal available till 08-06-2025
4 total number of authors per manuscript0 $

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Journal’s subject area:
Experimental and Cognitive Psychology;
Behavioral Neuroscience;
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Abstract:
Early-life adverse events exert persistent effects on brain functions and may increase the risk of psychopathology in adulthood. However, the underlying mechanism remains unclear. The purpose of our study was to study the long-lasting effects of maternal deprivation (MD) on depression-related behaviors and microtubule dynamics, and to illuminate the underlying molecular mechanism.
Keywords:
AKT; Cytoskeleton; Maternal deprivation; Microtubule dynamics; Neuroplasticity; P-CRMP2

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