#9377. Pre-Exposure Prophylaxis (PrEP) Dissemination: Adapting Diffusion Theory to Examine PrEP Adoption

November 2026publication date
Proposal available till 18-05-2025
4 total number of authors per manuscript5500 $

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Journal’s subject area:
Social Psychology;
Public Health, Environmental and Occupational Health;
Infectious Diseases;
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Abstract:
PrEP adoption among men-who-have-sex-with-men (AAMSM) remains low. We applied the Diffusion-of-Innovations (DOI) theory to understand PrEP adoption processes among young HIV-negative/status unknown AAMSM. Quantitative and qualitative analyses were used to examine predictors of PrEP diffusion stages. Most AAYMSM were in the persuasion stage (PrEP-aware, hadn’t adopted; 72.4%). Our results suggest that model antecedents are DOI stage-specific. PrEP awareness (knowledge stage) was associated with lower levels of social stigma (p <.03) and greater health literacy (p <.05), while sexual risk (p <.03) and education (p <.03) predicted PrEP adoption (12.2%). PrEP efficacy and side effects were primary innovation characteristics influencing adoption receptivity in the persuasion stage. Interventions to improve PrEP diffusion should be tailored to stage-specific antecedents depending on how a community is stratified across the DOI stages.
Keywords:
Diffusion; HIV/AIDS; Social stigma

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