#8791. Shigella ubiquitin ligase IpaH7.8 targets gasdermin D for degradation to prevent pyroptosis and enable infection

November 2026publication date
Proposal available till 29-05-2025
4 total number of authors per manuscript4500 $

The title of the journal is available only for the authors who have already paid for
Journal’s subject area:
Virology;
Parasitology;
Microbiology;
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Abstract:
Here, we investigate how the inhibition of pore-forming protein gasdermin D (GSDMD) affects the human body. Different inhibitors were considered. The adverse consequences of their use were outlined.
Keywords:
GSDMD; inflammasome; proteasome; pyroptosis; Shigella; ubiquitin ligase; virulence

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