#8595. A method for determination of aldosterone concentrations of six adrenal venous serum samples during a single LC/ESI-MS/MS run using a sextet of Girard reagents
March 2027 | publication date |
Proposal available till | 30-05-2025 |
4 total number of authors per manuscript | 6020 $ |
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Journal’s subject area: |
Medicine (all); |
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Abstract:
In this study, a stable isotope-dilution LC/ESI-MS/MS-based method was developed and validated for the determination of the ALD concentrations of the six ssAVS serum samples during a single run. A sextet of Girard reagents was used to convert ALD to the derivatives having different masses for each sample.
Keywords:
Aldosterone; Girard hydrazone; Primary aldosteronism; Sample-sextuplex method; Single LC/ESI-MS/MS run; Super-selective adrenal venous sampling
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