#8595. A method for determination of aldosterone concentrations of six adrenal venous serum samples during a single LC/ESI-MS/MS run using a sextet of Girard reagents

March 2027publication date
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Medicine (all);
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Abstract:
In this study, a stable isotope-dilution LC/ESI-MS/MS-based method was developed and validated for the determination of the ALD concentrations of the six ssAVS serum samples during a single run. A sextet of Girard reagents was used to convert ALD to the derivatives having different masses for each sample.
Keywords:
Aldosterone; Girard hydrazone; Primary aldosteronism; Sample-sextuplex method; Single LC/ESI-MS/MS run; Super-selective adrenal venous sampling

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