#8544. Jujuboside B induces mitochondrial-dependent apoptosis in colorectal cancer through ROS-mediated PI3K/Akt pathway in vitro and in vivo

October 2026publication date
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Journal’s subject area:
Food Science;
Medicine (miscellaneous);
Nutrition and Dietetics;
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Abstract:
In this paper, we provide evidence that Zizyphus jujuba can be used for the prevention and treatment of colorectal cancer, owing to the apoptosis-inducing effect of Jujube seed extract on colorectal cancer cells. We also provide a description of the extract mechanism.
Keywords:
Apoptosis; Colorectal cancer; Jujuboside B; PI3K/Akt; Saponin

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