#8404. Dedifferentiated liposarcoma with abrupt transition of low-grade and high-grade dedifferentiation: A rare case report

October 2026publication date
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Medicine (all);
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Abstract:
In affected patients, dedifferentiated liposarcoma typically manifests as the dedifferentiation of high-grade histological morphology, but it may also manifest as the dedifferentiation of low-grade histological morphology. In some cases, unique histological or immunophenotypic characteristics are observed. We describe, herein, a rare case of dedifferentiated liposarcoma, in which the high-grade and low-grade dedifferentiated components coexisted with a relatively sharp transition in pathology.
Keywords:
dedifferentiation; histopathology; liposarcoma; magnetic resonance imaging; neoplasm

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