#8112. Amphibian resistance to chytridiomycosis increases following low-virulence chytrid fungal infection or drug-mediated clearance

October 2026publication date
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Journal’s subject area:
Ecology;
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Abstract:
Amphibian biodiversity is experiencing ongoing declines due in part to the infectious disease, chytridiomycosis. Efforts to mitigate the effects of the causal agent of chytridiomycosis, Batrachochytrium dendrobatidis (Bd), in the wild have not been wholly effective. Translocations are an important management tool for amphibians, and immunizations represent a possible strategy for preparing amphibians for release across a landscape where Bd exists. We evaluated the utility of using an isolate of Bd that was shown to be hypovirulent to the relict leopard frog Rana onca as a transmissible inoculum for promoting chytridiomycosis resistance.
Keywords:
amphibian disease; Batrachochytrium dendrobatidis; disease mitigation; frog conservation; fungal vaccine; itraconazole; leopard frogs; transmissible vaccine

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