#7816. Utility of TPP-manufactured biophysical restrictions to probe multiscale cellular dynamics

October 2026publication date
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Journal’s subject area:
Biology
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Abstract:
Biophysical restrictions regulate protein diffusion, nucleus deformation, and cell migration, which are all universal and important processes for cells to perform their biological functions. However, current technologies addressing these multiscale questions are extremely limited. Herein, through two-photon polymerization (TPP), we present the precise, low-cost, and multiscale microstructures (micro-fences) as a versatile investigating platform.
Keywords:
Cell-climbing ability; Micro-fence; Multiscale; Nucleus mechanical bending; Protein diffusion

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