#7594. The use of a novel deer antler decellularized cartilage-derived matrix scaffold for repair of osteochondral defects

October 2026publication date
Proposal available till 20-05-2025
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Journal’s subject area:
Environmental Engineering;
Biomedical Engineering;
Molecular Biology;
Cell Biology;
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Abstract:
The physiologic regenerative capacity of cartilage is severely limited. Current studies on the repair of osteochondral defects (OCDs) have mainly focused on the regeneration of cartilage tissues. The antler cartilage is a unique regenerative cartilage that has the potential for cartilage repair. Antler decellularized cartilage-derived matrix scaffolds (adCDMs) were prepared by combining freezing-thawing and enzymatic degradation. Their DNA, glycosaminoglycans (GAGs), and collagen content were then detected.
Keywords:
Antler cartilage; Cartilage-derived matrix scaffolds; Decellularization; Osteochondral defect; Tissue engineering

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