#6022. Humans and machines in biomedical knowledge curation: hypertrophic cardiomyopathy molecular mechanisms’ representation

July 2026publication date
Proposal available till 28-05-2025
4 total number of authors per manuscript0 $

The title of the journal is available only for the authors who have already paid for
Journal’s subject area:
Computational Mathematics;
Computational Theory and Mathematics;
Computer Science Applications;
Genetics;
Biochemistry;
Molecular Biology;
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Abstract:
Background: Biomedical knowledge is dispersed in scientific literature and is growing constantly. Curation is the extraction of knowledge from unstructured data into a computable form and could be done manually or automatically. Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disease, with genotype–phenotype associations still incompletely understood. We compared human- and machine-curated HCM molecular mechanisms’ models and examined the performance of different machine approaches for that task.
Keywords:
Automated curation; Curation; Data mining; Disease maps; Hypertrophic cardiomyopathy; Knowledge graphs; Signaling pathways

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