#5985. Characterizing interdisciplinarity in drug research: A translational science perspective

August 2026publication date
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Journal’s subject area:
Medicine
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Abstract:
Background: Despite the significant advances in life science, it still takes decades to translate a basic drug discovery into a cure for human disease. To accelerate the process from “bench-to-bedside”, interdisciplinary research (especially research involving both basic research and clinical research) has been strongly recommend by many previous studies. However, the patterns and the roles of the interdisciplinary characteristics in drug research have not been deeply examined in extant studies. Objective: The purpose of this study was to characterize interdisciplinarity in drug research from the perspective of translational science, and to examine the role of different kinds of interdisciplinary characteristics in translational research for drugs. Methods: In this paper, we analyze the interdisciplinary of drug research from a novel bibliometric perspective, i.e., a translational science perspective. 18 FDA approved drugs belonging to 6 categories are used as the research proxies. We propose four bibliometric indicators (i.e., Diversity of Research, Symmetry of Research, Persistence of Research and Stability of Research) for characterizing interdisciplinarity in drug research at both the macro and micro levels. We also design a bibliometric indicator (i.e., Translation Intensity) for quantifying the result of a drugs translation. Correlation analysis was also used to examine the relationships between these interdisciplinary characteristics of drug research and the translation intensity of drugs.
Keywords:
Drug Research; Interdisciplinarity; Persistence; Scientometrics; Stability; Translational science

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