#3916. The associations between asymmetric handgrip strength and chronic disease status in american adults: Results from the national health and nutrition examination survey

September 2026publication date
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Medicine
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Abstract:
This research examined the associations between asymmetric handgrip strength (HGS) and multimorbidity in adults. Secondary analyses of data from persons aged at least 40 years from the 20XX–20XX and 20XX–20XX waves of the National Health and Nutrition Examination Survey were conducted. Adults with the presence of the following conditions had multimorbidity: cardiovascular disease, chronic obstructive pulmonary disease, chronic kidney disease, asthma, arthritis, cancer, obesity, stroke, hypertension, high cholesterol, and diabetes. Of the n = 3483 participants included, n = 2700 (77.5%) had multimorbidity. Relative to individuals without asymmetry, adults with asymmetric HGS had 1.31 (95% confidence interval (CI): 1.03–1.67) greater odds for multimorbidity. Moreover, persons with HGS asymmetry had 1.22 (CI: 1.04–1.44) greater odds for accumulating morbidities. providers should recommend healthy behaviors for reducing asymmetries to improve muscle function and mitigate morbidity risk after completing asymmetry screenings.
Keywords:
Chronic disease; Comorbidity; Epidemiologic research design; Muscle strength; Screening

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