#3515. The relationship between cognition and functioning in schizophrenia: A semi-systematic review

October 2026publication date
Proposal available till 30-05-2025
4 total number of authors per manuscript0 $

The title of the journal is available only for the authors who have already paid for
Journal’s subject area:
Linguistics and Language;
Language and Linguistics;
Developmental and Educational Psychology;
Experimental and Cognitive Psychology;
Cognitive Neuroscience;
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Abstract:
In schizophrenia, impairments in neurocognition (NC) and social cognition (SC) are associated with reduced functional capacity (FC) and poor real-world functioning (RWF). In this semi-systematic review, we examined this association across a range of research questions. After screening of journal titles, abstracts and full-texts, we included 564 citations, of which 44 (26 primary studies, 15 systematic reviews and 3 narrative reviews) were prioritized for reporting. Cognitive remediation improved RWF functioning, especially when it was combined with psychosocial rehabilitation. SC mediated the relationship of NC with functioning. Other factors involved included severity of cognitive dysfunction, metacognition, depression and choice of RWF instrument. The advantage of adjunctive psychosocial rehabilitation, the role of relevant moderating and mediating variables, and the challenges with RWF instrument selection.
Keywords:
Cognitive impairment; Functional capacity; Real-world functioning; Schizophrenia

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