#3203. Brain changes associated with impaired attention function in chronic pain

August 2026publication date
Proposal available till 27-05-2025
4 total number of authors per manuscript0 $

The title of the journal is available only for the authors who have already paid for
Journal’s subject area:
Arts and Humanities (miscellaneous);
Developmental and Educational Psychology;
Experimental and Cognitive Psychology;
Neuropsychology and Physiological Psychology;
Cognitive Neuroscience;
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Abstract:
Attention function is important in chronic pain, with the pathology of chronic pain closely associated with cognitive–emotional components. The present research used the method of functional connectivity analysis for resting-state fMRI (rs-fMRI) data and the Attention Network Test-Revision (ANT-R) to clarify the attention-related pathology of chronic pain. We performed rs-fMRI and ANT-R on a group of 26 chronic pain. A significant group difference in validity effects, a component of ANT-R, emerged, and the chronic pain group exhibited slower reaction times. Decreased brain connectivity of the left insula and left frontal regions was confirmed in chronic pain patients, and connectivity was negatively correlated with validity effects. The research concludes that poor control of attention function results from deficits of functional connectivity in the left insula and left frontal regions in chronic pain.
Keywords:
Attention network test; Chronic pain; Insula; Resting-state fMRI

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