#11564. The Lady from Basels Barf?sserkirche – Molecular confirmation of the Mummys identity through mitochondrial DNA of living relatives spanning 22 generations

August 2026publication date
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Journal’s subject area:
Law;
Pathology and Forensic Medicine;
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Abstract:
The identity of the mummified Lady from the Barfüsser Church in Basel, Switzerland has been unsolved for decades, despite the prominent location of the burial place in front of the choir screen. A recent multidisciplinary research approach came up with a possible candidate, Anna Catharina Bischoff who died in Basel in 1787 with an age of 69 years (1719–1787). In this study we compare the ancient mitochondrial DNA of the mummy recovered from a premolar to the mitochondrial DNA of these three candidates. Initially the mitochondrial hypervariable regions I and II of the living individuals were screened using the Sanger sequencing method. This was followed by a mitochondrial capture approach and next generation sequencing to enrich for the whole mitochondrial genome of the mummy and one living person. A full mitochondrial genome has been recovered of both individuals sharing an identical haplotype.
Keywords:
Ancient DNA; Genealogy; Identity reconstruction; MtDNA capture; Mummy

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