#11425. Strategies for studying bone loss in microgravity

August 2026publication date
Proposal available till 19-05-2025
4 total number of authors per manuscript0 $

The title of the journal is available only for the authors who have already paid for
Journal’s subject area:
Aerospace Engineering;
Radiation;
Radiology, Nuclear Medicine and Imaging;
Human Factors and Ergonomics;
Medicine (miscellaneous);
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Abstract:
NASA has recently completed several long-duration missions to the International Space Station and is solidifying plans to return to the Moon, with an eye toward Mars and beyond. The cardiovascular system may be especially vulnerable due to the combined impacts of space radiation exposure, lack of gravity, and other spaceflight hazards. On Earth, the risk for cardiovascular disease (CVD) following moderate to high radiation doses is well-established from clinical, environmental, and occupational exposures (largely from gamma- and x-rays). Less is known about CVD risks associated with high-energy charged ions found in space and increasingly used in radiotherapy applications on Earth, making this a critical area of investigation for occupational radiation protection. Assessing CVD risk is complicated by its multifactorial nature, where an individuals risk is strongly influenced by factors such as family history, blood pressure, and lipid profiles. The tools improve clinical decision-making, personalize care, and support primary prevention of CVD. This approach is a first step in using personalized medicine for radiation risk assessment to support safe and productive spaceflight and long-term quality of life for NASA astronauts.
Keywords:
Сardiovascular system; space; radiation doses; radiation protection; astronauts

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