#6246. Light express

September 2026publication date
Proposal available till 18-05-2025
4 total number of authors per manuscript0 $

The title of the journal is available only for the authors who have already paid for
Journal’s subject area:
Applied Mathematics;
Modeling and Simulation;
Computer Science Applications;
Biochemistry, Genetics and Molecular Biology (all);
Drug Discovery;
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Abstract:
Each of us is a unique individual despite carrying almost the same genetic information as anyone else. Zooming in into our body, we find the same pattern: all cells share the same genome, and yet they look and behave differently. The process of gene expression is the reason behind this fascinating phenomenon whereby the same genome is translated in different sets of molecules being present in the cell at any given time. The ability to precisely control this process endows researchers with great power, not only for basic science purposes but also for biotechnological and biomedical applications. In this review, we will discuss the current arsenal of tools that consent to control gene expression using light as the external trigger. These tools are, in most cases, preferable to those based on chemical triggers owing to the many favorable properties of light, foremost its spatial confineability and easy removal.
Keywords:
Control; Gene expression; Light-inducible gene expression; Optogenetics; Protein engineering; Protein–protein interaction

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